Relative paradigms between autoantibodies in lupus and autoantibodies in cancer
نویسندگان
چکیده
منابع مشابه
Generation and Evaluation of Monoclonal Autoantibodies in Systemic Lupus Erythematosis
Three murine monoclonal anti-ssDNA autoantibodies have been produced by fusion of spleen cells from NZB/NZW F1 hybrid mice with Sp2/0-Ag 14 murine myeloma cells. Specificity studies characterizing monoclonal anti - ssDNA autoantibodies revealed binding patterns for nucleotides. Clone E-4-1 showed preferential binding with mono-di-and polyguanosine. Clones E-4-4 and E-11-1 specitically bound mon...
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BACKGROUND AND AIM The sensitivity and specificity of biomarkers used for predicting peripheral neuropathy in patients with systemic lupus erythematosus (SLE) and nephritis (SLE-LN) remain unsatisfactory. This study aimed to determine the autoantibodies levels in SLE-LN patients with peripheral neuropathy. METHODS Data of 559 SLE-LN patients were collected retrospectively, including titers of...
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_______________________________ Correspondence to: Daniela Monova, 24 Veliko Turnovo str, Sofia 1504, Bulgaria, tel++3598437705 e-mail: [email protected] Autoantibodies Against C1q: View on Association Between Systemic Lupus Erythematosus Disease Manifestation and C1q autoantibodies D. Monova, S. Monov, K. Rosenova, T. Argirova Medical University Sofia, Department of Internal Medicine, Sofia ...
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Autoantibodies may be found years before an autoimmune disease becomes clinically apparent. For systemic lupus erythematosus (SLE), those to RNA-binding proteins, to phospholipids, and to double-stranded DNA, in particular, have been found in sera of SLE patients years before the diagnosis was made. New data now show in an unbiased way that, in patients with early SLE, no single antibody class ...
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ژورنال
عنوان ژورنال: Clinical & Experimental Immunology
سال: 2003
ISSN: 0009-9104
DOI: 10.1046/j.1365-2249.2003.02259.x